Informação sobre produto
Nome:
Purvalanol A
Sinónimos:
- (2R)-2-({6-[(3-Chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methylbutan-1-ol
- (2R)-2-[[6-(3-Chloroanilino)-9-isopropyl-purin-2-yl]amino]-3-methyl-butan-1-ol
- (2R)-2-[[6-(3-Chloroanilino)-9-propan-2-ylpurin-2-yl]amino]-3-methylbutan-1-ol
- (2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol
- (R)-Purvalanol A
- 1-Butanol, 2-[[6-[(3-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-, (2R)-
- Ng 60
Descrição:
Purvalanol A is a chemotherapeutic drug that inhibits the survivin protein. This protein is an important regulator of cellular apoptosis and has been shown to be overexpressed in many cancers, including melanoma, ovarian cancer and breast cancer. Purvalanol A has significant cytotoxic activity against cells with high survivin expression. Purvalanol A also blocks the ABCG2 transporter, which transports drugs across the cell membrane, and prevents transcriptional regulation by taxol. Purvalanol A induces pluripotent cells to differentiate into neural cells and may be useful for treating Parkinson's disease as well as carcinomas.
Aviso:
Os nossos productos estão destinados exclusivamente para uso em laboratório. Para qualquer outra aplicação, por favor entre em contacto.
Marca:
Biosynth
Armazenamento a longo prazo:
Notas:
Propriedades químicas
Peso molecular:
388.9 g/mol
Fórmula:
C19H25ClN6O
Pureza:
Min. 95%
MDL:
Ponto de fusão:
Ponto de ebulição:
Ponto de inflamação:
Densidade:
Concentração:
EINECS:
Merck:
Código HS:
