(S)-6,7-Dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-5H-imidazo[2,1-b][1,3]oxazine

CAS: 187235-37-6

Ref. 3D-FP26721

Informação sobre produto

• Nome: (S)-6,7-Dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-5H-imidazo[2,1-b][1,3]oxazine
• Sinónimos: (6S)-6,7-Dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-5H-imidazo[2,1-b][1,3]oxazine Pretomanid(S)-PA 824, (6S)-2-Nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine, (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine, (6S)-6,7-Dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-5H-imidazo[2,1-b][1,3]oxazine, (S)-2-Nitro-6-((4-(trifluoromethoxy)benzyl)oxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine, (S)-6-[[4-(Trifluoromethoxy)benzyl]oxy]-6,7-dihydro-2-nitro-5H-imidazo[2,1-b][1,3]oxazine, (S)-Pa 824, 5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-, (6S)-, 5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-, (S)-, Pa-824, Pretomanid

Descrição

(S)-6,7-Dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-5H-imidazo[2,1-b][1,3]oxazine is a prodrug that is converted to pyrazinoic acid in vivo. It has been shown to have a matrix effect on the bowel wall and can be used for the treatment of infectious diseases such as pandemic influenza. The optimum concentration of (S)-6,7-dihydro-2-nitro-6-[(4-(trifluoromethoxy)phenyl)methoxy]-5H-[1,3]imidazol[2,1-b][1]oxazine for activity is unknown but it has been shown to inhibit the polymerase chain reaction at concentrations up to 500 μM. The drug binds with high affinity to DNA and RNA. It

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 359.26 g/mol
• Fórmula: C₁₄H₁₂F₃N₃O₅
• Pureza: Min. 98 Area-%
• Cor/forma: Off-White Slightly Yellow Powder