Prochlorperazine sulfoxide

CAS: 10078-27-0

Ref. 3D-FP27168

Informação sobre produto

• Nome: Prochlorperazine sulfoxide
• Sinónimos: 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine 5-oxide, 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine 5-Oxide, 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine 5-oxide
• CAS: 10078-27-0

Descrição

Prochlorperazine sulfoxide is a prodrug of prochlorperazine, which is used as an antiemetic agent. It has a chemical stability that is greater than prochlorperazine and has shown resistance to cancer cells in clinical studies. Prochlorperazine sulfoxide is not an analog of any other drug. The LC-MS/MS method for quantitating the drug in plasma samples was recently calibrated using pharmacopeia standards. The calibration curve was linear over the concentration range 0.05-10 ng/mL with a correlation coefficient of 0.9998 and precision (RSD) of 1%.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 389.94 g/mol
• Fórmula: C₂₀H₂₄ClN₃OS
• Pureza: Min. 95%
• InChI: InChI=1S/C20H24ClN3OS/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)26(25)20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3/t26-/m0/s1
• Chave InChI: InChIKey=AZGYHFQQUZPAFZ-SANMLTNESA-N
• SMILES: CN1CCN(CCCN2c3ccccc3[S@](=O)c3ccc(Cl)cc32)CC1