(-)-Praeruptorin A

CAS: 14017-71-1

Ref. 3D-FP42769

Informação sobre produto

• Nome: (-)-Praeruptorin A

Descrição

(-)-Praeruptorin A is a coumarin derivative that inhibits protein synthesis and has been shown to have anti-inflammatory and antihypertensive activities. (-)-Praeruptorin A is a competitive inhibitor of human cyp3a4 (CYP3A4) with an IC50 value of 0.1 µg/mL in vitro. The IC50 of this compound for rat liver microsomes was determined to be 10.4 µg/mL, which indicates that (-)-praeruptorin A is also a substrate for CYP3A4. This coumarin derivative also inhibits the activity of creatine kinase in vitro and increases the intracellular calcium concentration in cells.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 386.4 g/mol
• Fórmula: C₂₁H₂₂O₇
• Pureza: Min. 95%
• Cor/forma: Powder