1-Pyridin-3-yl-piperazine dihydrobromide
CAS: 67980-77-2
Ref. 3D-FP51023
| 1g | A consultar | ||
| 2g | A consultar | ||
| 5g | A consultar | ||
| 10g | A consultar | ||
| 500mg | A consultar |
Informação sobre produto
- 1-Pyridin-3-ylpiperazine
1-Pyridin-3-yl-piperazine dihydrobromide is a conformationally restricted, irreversible inhibitor of tyrosine protein kinases. It inhibits the activity of many tyrosine protein kinases from different families, including c-Src, c-Abl, and PDGF receptor. The compound has been shown to be effective in vivo against tumor cells in mouse models of hematological malignancies and melanoma. 1-Pyridin-3-yl-piperazine dihydrobromide is also active against a number of human cancer cell lines in vitro. The compound binds to the ATP binding site on the enzyme's active site and inhibits the catalytic phosphorylation reaction by competitive inhibition.
Propriedades químicas
Consulta técnica sobre: 3D-FP51023 1-Pyridin-3-yl-piperazine dihydrobromide
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