Informação sobre produto
ZL0420 is a bromodomain inhibitor that binds to the bromodomain of toll-like receptor 3 (TLR3) and TLR4. ZL0420 has been shown to inhibit the response to TLR3 and TLR4 stimulation in vitro and in vivo in mice. This inhibition leads to a decrease in the production of inflammatory cytokines and chemokines, which reduces inflammation. ZL0420 also modulates the expression of genes involved in cancer development, mesenchymal transition, and muscle cell response. It inhibits the activity of a number of proteins including histone deacetylases, protein kinase C, NF-κB, JNK, TNF receptor I/II, TRAF6, Janus kinase 2 (JAK2), and phosphoinositide 3-kinase (PI3K). ZL0420 has not yet been tested for toxicity or efficacy in humans.
Propriedades químicas
Consulta técnica sobre: 3D-FPD49680 ZL0420
Se desejar solicitar um orçamento ou fazer uma encomenda, por favor, adicione os produtos ao seu carrinho e depois solicite um orçamento ou encomenda a partir do carrinho. É mais rápido, mais barato e poderá beneficiar-se dos descontos e outras vantagens disponíveis.
