Ruxolitinib

CAS: 941678-49-5

Ref. 3D-FR27771

Informação sobre produto

• Nome: Ruxolitinib
• Sinónimos: (β-R)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrileINCB 018424, (3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile, (Betar)-Beta-Cyclopentyl-4-(7H-Pyrrolo(2,3-D)Pyrimidin-4-Yl)-1H-Pyrazole-1-Propanenitrile, (R)-3-[4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-cyclopentylpropanenitrile, (βR)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile, 1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, (βR)-, Inc 424, Incb-018424, R-Incb018424, R-Ruxolitinib, Ruxolitinib (INCB 018424), Ruxolitinib phosphate salt
• CAS: 941678-49-5

Descrição

Ruxolitinib is a janus tyrosine kinase inhibitor active specifically on sub-types JAK1 and JAK2 with IC50 values in the nanomolar range. JAK1 and JAK2 are kinases involved in the regulation of hematopoiesis. Clinically applied to the treatment of intermediate and high-risk myelofibrosis, ruxolitinib is usually well tolerated by patients.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 306.37 g/mol
• Fórmula: C₁₇H₁₈N₆
• Pureza: Min. 95%
• Cor/forma: White Powder