Sodium N-(6-chloropyridazin-3-yl)sulphanilamidate

CAS: 23282-55-5

Ref. 3D-FS46701

Informação sobre produto

• Nome: Sodium N-(6-chloropyridazin-3-yl)sulphanilamidate
• Sinónimos: Sulfachloropyridazine sodium, 201-269-9, 3-Chloro-6-sulfanilamidopyridazine, 3-Sulfanilamido-6-chloropyridazine, 4-Amino-N-(6-chlor-3-pyridazinyl)benzolsulfonamid, 4-Amino-N-(6-chloro-3-pyridazinyl)benzenesulfonamide, 4-amino-N-(6-chloropyridazin-3-yl)benzenesulfonamide, Benzenesulfonamide, 4-amino-N-(6-chloro-3-pyridazinyl)-, monosodium salt, Benzenesulfonamide, 4-amino-N-(6-chloro-3-pyridazinyl)-, sodium salt (1:1), Prinzone, Sodium [(4-Aminophenyl)Sulfonyl](6-Chloropyridazin-3-Yl)Azanide, Sodium sulfachloropyridazine, Sodium sulfachlorpyridazine, Spdz, Sulfachloropyridazine Sodium, Sulfachlororyridazine sodium, Sulfachlorpyridazine Sodium, Sulfachlorpyridazine sodium salt, Sulfanilamide, N¹-(6-chloro-3-pyridazinyl)-, monosodium salt, Vetisulid, benzenesulfonamide, 4-amino-N-(6-chloro-3-pyridazinyl)-

Descrição

Sodium N-(6-chloropyridazin-3-yl)sulphanilamidate (NPS) is a sulfa drug that has been shown to have an effect on the enzyme activities of some endoparasites, such as Giardia lamblia and Entamoeba histolytica. The active form of NPS is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. It also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 306.7 g/mol
• Fórmula: C₁₀H₈ClN₄O₂SNa
• Pureza: Min. 95%