2-[[3-(Trifluoromethyl)phenyl]amino]-3-Pyridinecarboxylic acid 2-(4-morpholinyl)ethyl ester hydrochloride

CAS: 23476-71-3

Ref. 3D-FT102761

Informação sobre produto

• Nome: 2-[[3-(Trifluoromethyl)phenyl]amino]-3-Pyridinecarboxylic acid 2-(4-morpholinyl)ethyl ester hydrochloride
• Sinónimos: 2-(Morpholin-4-Yl)Ethyl 2-{[3-(Trifluoromethyl)Phenyl]Amino}Pyridine-3-Carboxylate Hydrochloride (1:1), 2-Morpholinoethyl 2-(alpha,alpha,alpha-trifluoro-m-toluidino)nicotinate monohydrochloride, 3-Pyridinecarboxylic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-, 2-(4-morpholinyl)ethyl ester, hydrochloride (1:1), 3-Pyridinecarboxylic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-, 2-(4-morpholinyl)ethyl ester, monohydrochloride, 4-Morpholineethanol, 2-(α,α,α-trifluoro-m-toluidino)nicotinate (ester), monohydrochloride, Nicotinic acid, 2-(α,α,α-trifluoro-m-toluidino)-, 2-morpholinoethyl ester, monohydrochloride

Descrição

2-[[3-(Trifluoromethyl)phenyl]amino]-3-Pyridinecarboxylic acid 2-(4-morpholinyl)ethyl ester hydrochloride (2-TCPAEM) is a β-cyclodextrin derivative that is a potent anti-inflammatory and analgesic drug. It has been shown to be more effective than indomethacin in animal models of inflammation. 2-TCPAEM binds to cyclodextrins, which are water soluble carbohydrates, and the complex is more soluble in water and less toxic than indomethacin. The molecular modeling studies have shown that 2-TCPAEM binds to the hydrophobic pocket of cyclodextrin, making it an analogue of phenylbutazone. The analogous compounds have been synthesized using β-cyclodextrin as a template for the synthesis of 2-TCPAEM. The experimental yields have been found to be 85

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 431.84 g/mol
• Fórmula: C₁₉H₂₁ClF₃N₃O₃
• Pureza: Min. 95%