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N-[2-(trifluoromethyl)phenyl]acetamide
CAS: 344-62-7
Ref. 3D-FT105343
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Informação sobre produto
- 2-Acetamidobenzotrifluoride
- 2-Acetamidotrifluoromethylbenzene
- 2-Trifluoromethylacetanilide
- Acetamide, N-[2-(trifluoromethyl)phenyl]-
- N-[2-(Trifluoromethyl)phenyl]acetamide
- NSC 88329
- o-Acetotoluidide, α,α,α-trifluoro-
- o-Trifluoromethylpropionanilide
- α,α,α-Trifluoro-o-acetotoluidide
N-[2-(trifluoromethyl)phenyl]acetamide is a synthetic compound that has been shown to be an effective inhibitor of the enzyme acetyl-CoA carboxylase (ACC). ACC catalyzes the conversion of acetyl-CoA and oxaloacetate to malonyl-CoA and pyruvate. N-[2-(trifluoromethyl)phenyl]acetamide inhibits this reaction by binding to the active site of ACC, which prevents the formation of a thioester bond between coenzyme A and oxaloacetate. N-[2-(trifluoromethyl)phenyl]acetamide has been shown to inhibit tumor growth in vitro and in vivo, as well as reduce weight gain in mice fed a high-fat diet. It also suppresses lipid accumulation by inhibiting ACC activity.
Propriedades químicas
Consulta técnica sobre: 3D-FT105343 N-[2-(trifluoromethyl)phenyl]acetamide
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