H-Trp-Leu-OH
CAS: 13123-35-8
Ref. 3D-FT108197
1g | 669,00 € | ||
50mg | 343,00 € | ||
100mg | 430,00 € | ||
250mg | 478,00 € | ||
500mg | 574,00 € |
Informação sobre produto
- L-Tryptophyl-L-leucine
- Tryptophylleucine
- (2S)-2-{[(2S)-2-ammonio-3-(1H-indol-3-yl)propanoyl]amino}-4-methylpentanoate
H-Trp-Leu-OH is a drug that has been shown to have high efficiency against cancer cells. It is also used as an experimental drug for the treatment of angiotensin II, which is a peptide hormone that regulates blood pressure and fluid balance in the body. H-Trp-Leu-OH has been shown to be hydrolyzed by thermolysin and efficiently catalyzed by serine proteases. This drug binds to the active site of angiotensin converting enzyme (ACE) in order to inhibit ACE activity. The fluorescence spectroscopic assay was used to measure the binding affinity between H-Trp-Leu-OH and angiotensin II, which was found to be linear with respect to concentration. Kinetic parameters were studied using a spectrofluorometric assay, which showed that H-Trp-Leu-OH inhibits ACE activity at concentrations of 1 uM or above.
Propriedades químicas
Consulta técnica sobre: 3D-FT108197 H-Trp-Leu-OH
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