1,3-Thiazol-4-ylmethylamine dihydrochloride
CAS: 16188-30-0
Ref. 3D-FT116097
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Informação sobre produto
- 4-Thiazolemethanamine
- 4-(Chloromethyl)-1,3-Thiazole
1,3-Thiazol-4-ylmethylamine dihydrochloride (1,3-TMA) is a bactericidal agent that belongs to the class of arylhydrazones. It has been shown to be fungicidal against Aspergillus niger and Byssochlamys fulva. 1,3-TMA has also been shown to have bactericidal activity against Bacillus subtilis, Staphylococcus aureus, and Escherichia coli. This drug is active against many Gram-positive bacteria at concentrations as low as 0.01 mg/mL. 1,3-TMA binds to the bacterial cell wall by competitive inhibition of the enzyme cell wall synthesis that is required for cell wall biosynthesis and protein synthesis. The chloride ion in 1,3-TMA may act as an electron donor for the oxidation of benzoyl chloride by cytochrome P450 enzymes in bacteria.
Propriedades químicas
Consulta técnica sobre: 3D-FT116097 1,3-Thiazol-4-ylmethylamine dihydrochloride
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