Thiazolidine-2,4-dione

CAS: 2295-31-0

Ref. 3D-FT16406

Informação sobre produto

• Nome: Thiazolidine-2,4-dione
• Sinónimos: 1,3-Thiazolidine-2,4-dione2,4-Thiazolidinedione, 1,3-Thiazolidine-2,4-Dione, 2,4(3H,5H)-Thiazoledione, 2,4-Dioxo-1,3-thiazolidine, 2,4-Dioxothiazolidine, 2,4-Thiadolidinedione, 2-Hydroxy-4,5-dihydro-1,3-thiazol-4-one, 2-Thiazolin-4-one, 2-hydroxy-, Nsc 6745, Otava-Bb Bb7112440002, TZD, Thiazole-2,4-dione, Thiazolidin-2,4-dion, Thiazolidin-2,4-dione, Thiazolidinedione, Thiazolidinedione-2,4, Tiazolidina-2,4-Diona, Timtec-Bb Sbb000047, U 25560, 2,4-Thiazolidinedione

Descrição

Thiazolidine-2,4-dione (THZ) is a drug that has been shown to be an orally active, anti-inflammatory agent with postprandial blood glucose lowering properties. It inhibits the nuclear factor kappa B (NF-κB) binding activity and suppresses inflammation in vitro and in vivo. THZ also has hypoglycemic effects and may be used as an oral hypoglycemic agent for the treatment of diabetes mellitus type 2. THZ is not active against bowel disease or atherosclerosis. It interacts with other drugs, such as statins, which reduce its hypoglycemic effects. This drug also intercalates into DNA and binds to response elements related to inflammation and insulin signalling pathways.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 117.13 g/mol
• Fórmula: C₃H₃NO₂S
• Pureza: Min. 89.0%
• Cor/forma: Powder
• InChI: InChI=1S/C3H3NO2S/c5-2-1-7-3(6)4-2/h1H2,(H,4,5,6)
• Chave InChI: InChIKey=ZOBPZXTWZATXDG-UHFFFAOYSA-N
• SMILES: O=C1CSC(=O)N1