5,6,8,9-Tetrahydro-7H-dibenzo[c,g]carbazole

CAS: 117766-87-7

Ref. 3D-FT28118

Informação sobre produto

• Nome: 5,6,8,9-Tetrahydro-7H-dibenzo[c,g]carbazole
• Sinónimos: 6,7,8,9-Tetrahydro-5H-dibenzo[c,g]carbazole

Descrição

5,6,8,9-Tetrahydro-7H-dibenzo[c,g]carbazole is a synthetic compound that has cytotoxic and anticonvulsant properties. It binds to DNA and inhibits the synthesis of RNA in the ribosomes. 5,6,8,9-Tetrahydro-7H-dibenzo[c,g]carbazole has been shown to be active against epilepsy in mice. This drug also has activity against cancer cells in vitro and in vivo. The x-ray crystallography structure of 5,6,8,9-tetrahydro-7H-dibenzo[c,g]carbazole bound to DNA shows that it binds to the minor groove of DNA with two heterocyclic rings at opposite ends of the molecule forming an extended conformation with a hydrophobic pocket for binding dna.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 271.36 g/mol
• Fórmula: C₂₀H₁₇N
• Pureza: Min. 95%
• InChI: InChI=1S/C20H17N/c1-3-7-15-13(5-1)9-11-17-19(15)20-16-8-4-2-6-14(16)10-12-18(20)21-17/h1-8,21H,9-12H2
• Chave InChI: InChIKey=CHMSQWXOEBBYGI-UHFFFAOYSA-N
• SMILES: c1ccc2c(c1)CCc1[nH]c3c(c1-2)-c1ccccc1CC3