Tricosafluorododecanoic Acid

CAS: 307-55-1

Ref. 3D-FT60479

Informação sobre produto

• Nome: Tricosafluorododecanoic Acid
• Sinónimos: Perfluorododecanoic AcidPerfluorolauric AcidTricosafluorolauric Acid, 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Tricosafluorododecanoic acid, 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,12-Tricosafluorododecanoic acid, Dodecanoic acid, 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,12-tricosafluoro-, Dodecanoic acid, tricosafluoro-, PFDoDA, Perfluorododecanoic acid, Perfluorolauric acid

Descrição

Tricosafluorododecanoic Acid (TCDA) is a potent cytotoxic agent that has been shown to be effective in killing cancer cells. TCDA is a strong inducer of apoptosis and necrosis, which are processes that cause the death of cells. TCDA also induces cell cycle arrest by binding to mitochondrial membranes and inhibiting the flow of ions across the membrane, leading to a loss of mitochondrial membrane potential. This leads to an accumulation of intracellular calcium and activates signal pathways that activate the cell's death program. TCDA has been shown to have significant cytotoxicity against human breast cancer cells, with little toxicity against healthy human erythrocytes. TCDA is not active against bacteria or fungi, but it is highly toxic to certain protozoans such as Plasmodium falciparum. TCDA can be used as an effective treatment for cancer in combination with radiation therapy because it enhances the therapeutic effects of radiation on tum

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 614.1 g/mol
• Fórmula: C₁₂HF₂₃O₂
• Pureza: Min. 95%