Tetraphenylphosphonium Chloride
CAS: 2001-45-8
Ref. 3D-FT75406
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Informação sobre produto
- Chlorotetraphenylphosphorane
- Phosphonium, Tetraphenyl-, Hydrochloride
- Phosphonium, tetraphenyl-, chloride
- Phosphonium, tetraphenyl-, chloride (1:1)
- T 1735
- Tetra Phenyl Phosphonium Chloride
- Tetraphenyl phosphonium chloride
- Tetraphenylchlorophosphine
- Tetraphenylphosphanium chloride
- Tetraphenylphosponium Chloride
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Tetraphenylphosphonium Chloride is an antimicrobial agent that inhibits the growth of bacteria by binding to the cell nuclei. It has been shown to be active against both Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus. Tetraphenylphosphonium Chloride inhibits the synthesis of mitochondrial membrane potential, which leads to the inhibition of enzyme activities in mitochondria. This allows for use as an anti-cancer drug by inhibiting tumour cell proliferation. Tetraphenylphosphonium Chloride also binds to DNA and alters its structure, preventing transcription and replication. The x-ray crystal structures show that this compound binds to the phosphate group in DNA and interacts with DNA bases through hydrogen bonding interactions.
Propriedades químicas
Consulta técnica sobre: 3D-FT75406 Tetraphenylphosphonium Chloride
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