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Valine betaine is a dietary supplement that is used to increase the levels of this amino acid in the body. The most common use for valine betaine is to treat insulin resistance, which can lead to type 2 diabetes. Valine betaine has been shown to reduce insulin resistance in mammalian cells by inhibiting fatty acid synthesis and increasing glucose uptake. Valine betaine also inhibits the activity of cytochrome P450 enzymes, which are responsible for metabolizing drugs and toxins found in the liver. Valine betaine may also be beneficial for preventing kidney stones and lowering homocysteine levels as well as reducing cholesterol levels.