Glycyl-glycine 7-amido-4-methylcoumarin hydrochloride

CAS: 191723-65-6

Ref. 3D-G-6100

Informação sobre produto

• Nome: Glycyl-glycine 7-amido-4-methylcoumarin hydrochloride
• Sinónimos: Glycinamide, glycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, monohydrochloride, H-Gly-Gly-Amc Hcl, 1225: PN: WO2023172654 SEQID: 1233 claimed sequence, 555: PN: US20220128567 SEQID: 1233 claimed sequence, 555: PN: US20220178935 SEQID: 1233 claimed sequence

Descrição

Glycyl-glycine 7-amido-4-methylcoumarin hydrochloride (Gly-Gly-AMC) is a fluorescent compound that can be used as a probe for the transfer of glycine in the brain. Gly-Gly-AMC binds to Langerhans cells and is transferred by an anterograde axonal transport mechanism from the peripheral nervous system to the central nervous system. The binding of Gly-Gly-AMC to Langerhans cells has been shown to activate them, which induces the release of inflammatory mediators into the surrounding tissue. This activity may be due to increased levels of calcium ions, which are known to induce exocytosis in these cells. Glycine is also involved in depression and other mental disorders, as well as muscle and brain activity.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 325.75 g/mol
• Fórmula: C₁₄H₁₆ClN₃O₄