Simendan
CAS:
Ref. 3D-GFA74108
Informação sobre produto
Nome:Simendan
Marca:Biosynth
Descrição:Simendan is a calcium sensitizer that increases the sensitivity of the heart to calcium ions. It also has natriuretic peptide-like activity and increases levels of atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP). Simendan is available as a racemic mixture of two stereoisomers, levosimendan and dextrosimendan. It is used in veterinary medicine to treat congestive heart failure in dogs. Levosimendan is metabolized by hydrolysis into the active form, which binds to cardiac troponin C and stimulates the phosphorylation of myosin light chains. This leads to an increase in contractility, efficiency, and rate of relaxation of cardiac muscle cells. Simendan also has been shown to have effects on ventricular function, myocardial performance, blood pressure levels, and drug interactions with other medications.
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Propriedades químicas
Peso molecular:280.28 g/mol
Fórmula:C14H12N6O
Pureza:Min. 95%