PS-1145

CAS: 431898-65-6

Ref. 3D-GSA89865

Informação sobre produto

• Nome: PS-1145
• Sinónimos: N-(6-Chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide
• Marca: Biosynth
• Descrição: PS-1145 is a chemical inhibitor that belongs to the class of small molecule inhibitors. PS-1145 binds to the IL2 receptor and blocks the activation of BCL-2 protein, leading to cell death by inhibiting the production of proteins vital for cell division. It also inhibits inhibitory proteins such as IκBα and NEMO, which are important for NF-κB signaling. PS-1145 induces oxidative injury and caspase-independent cell death in cells by binding to DNA at response elements, thereby inhibiting transcriptional activity.

Propriedades químicas

• Peso molecular: 322.75 g/mol
• Fórmula: C₁₇H₁₁ClN₄O
• Pureza: Min. 95%