Informação sobre produto
N-(2-Methylphenyl)methanesulfonamide is a hydrogen bond donor and a potential drug candidate for the treatment of HIV. The compound has been shown to have potent anti-HIV activity, with IC50 values in the range of 10-20 μM. N-(2-Methylphenyl)methanesulfonamide binds to the viral envelope protein gp120, preventing it from binding to CD4 T cells and inhibiting HIV replication. It also interacts with amino acid residues on gp120 involved in stabilizing the virus particle and has been shown to inhibit the conformational changes associated with HIV assembly and release. These interactions are thought to be mediated by hydrogen bonding between the amide nitrogen of N-(2-methylphenyl)methanesulfonamide and various amino acid residues on gp120. This study shows that N-(2-methylphenyl)methanesulfonamide is a promising lead compound for future development as an anti
Propriedades químicas
Consulta técnica sobre: 3D-HAA02217 N-(2-Methylphenyl)methanesulfonamide
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