2-Aminomethyl-3-(4-methoxyphenyl)propionic acid
CAS: 682803-14-1
Ref. 3D-HCB80314
1g | 737,00 € | ||
100mg | 198,00 € |
Informação sobre produto
- 3-Amino-2-(4-methoxybenzyl)propanoic acid
- Benzenepropanoic acid, α-(aminomethyl)-4-methoxy-
2-Aminomethyl-3-(4-methoxyphenyl)propionic acid (2AMMPP) is an amide derivative of the β-amino acid, phenylalanine. It has been used in the treatment of rheumatoid arthritis and other disorders because it inhibits the formation of amyloid fibrils. 2AMMPP binds to the n-terminal region of a protein and prevents its aggregation into amyloid fibrils by binding to two adjacent hydrophobic residues on one side of the β-amino acid residue. Crystallographic studies have shown that 2AMMPP binds to a specific site on the protein. The binding site is located near a salt bridge between two amino acids and is stabilized by hydrogen bonding interactions with three water molecules.
2AMMPP also exhibits x-ray crystallography, birefringence, morphology, and staining properties as well as therapeutic effects for rhe
Propriedades químicas
Consulta técnica sobre: 3D-HCB80314 2-Aminomethyl-3-(4-methoxyphenyl)propionic acid
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