Albendazole sulfoxide

CAS: 54029-12-8

Ref. 3D-IA17259

Informação sobre produto

• Nome: Albendazole sulfoxide
• Sinónimos: Albendazole oxideRicobendazoleRS-8852, Albendazole S-oxide, Albendazole Sulfoxide, Carbamic acid, N-[6-(propylsulfinyl)-1H-benzimidazol-2-yl]-, methyl ester, Carbamic acid, [5-(propylsulfinyl)-1H-benzimidazol-2-yl]-, methyl ester, Methyl [5-(propylsulfinyl)-1H-benzimidazol-2-yl]carbamate, N-(4-hydroxyphenyl)methanesulfonamide, Ricobendazole, Rs 8852, Rycobendazole, methyl (5-propylsulfinyl-3H-benzoimidazol-2-yl)aminoformate, methyl [6-(propylsulfinyl)-1H-benzimidazol-2-yl]carbamate

Descrição

Albendazole sulfoxide is a sulfoxide of albendazole. The molecular docking analysis of the two molecules showed that the sulfoxide group is located in the same position as the hydroxyl group on albendazole. It has been shown that this replacement of hydroxyl with a sulfoxide group increases the solubility and stability of albendazole, which may be due to hydrogen bonding interactions between these groups. Albendazole sulfoxide has been shown to be an effective treatment for infections caused by parasites such as helminths. However, it should not be used in combination with drugs that are metabolized by cytochrome P450 enzymes because it can inhibit their activity.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 281.33 g/mol
• Fórmula: C₁₂H₁₅N₃O₃S
• Pureza: Min. 97 Area-%
• Cor/forma: White Powder