Informação sobre produto
- 3-Pyridinesulfonyl chloride, 4-chloro-
- 4-Chloro-3-pyridinesulfonyl chloride
- 4-Chloro-3-pyridinesulfonylchloride
- 4-Chloro-3-pyridinylsulfonyl chloride
- 4-Chloro-3-pyridylsulfonyl chloride
- 4-Chloro-3-pyridylsulfonylchloride
4-Chloropyridine-3-sulfonyl chloride is a thrombin inhibitor that has been discovered through the use of in vitro screening methods. It is a small molecule with lipophilic properties and oral bioavailability. This compound inhibits thrombin by binding to the active site of the enzyme, which prevents the formation of an enzyme-thrombin complex. The discovery was made using a pharmacophore-based approach and further modifications were made to improve its potency and increase its lipophilicity. This compound also exhibits an acceptable level of bioavailability in vivo, which may be due to its high solubility in water.
Propriedades químicas
Consulta técnica sobre: 3D-IBA26344 4-chloropyridine-3-sulfonyl chloride
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