Dehydro simvastatin

CAS: 210980-68-0

Ref. 3D-ID20948

Informação sobre produto

• Nome: Dehydro simvastatin
• Sinónimos: Simvastatin Impurity C
• CAS: 210980-68-0

Descrição

Dehydro simvastatin is a high-yielding, efficient, and selective synthesis of simvastatin. It is prepared from the commercially available (2S)-2-[(1E,3R)-3-hydroxybut-1-enyl]oxirane using a three-component reaction with chlorotrimethylsilane and sodium chloride to yield the desired product in good yields. The reaction can be performed in a variety of solvents including dichloromethane, chloroform, tetrahydrofuran, or methanol. Dehydro simvastatin has been used for pharmaceutical formulations as an active ingredient of HMG CoA reductase inhibitors. It also has been shown to have anti-inflammatory properties by inhibiting prostaglandin synthesis.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 400.55 g/mol
• Fórmula: C₂₅H₃₆O₄
• Pureza: Min. 95%
• Cor/forma: Colorless Powder