Dideiodo amiodarone

CAS: 23551-25-9

Ref. 3D-ID21728

Informação sobre produto

• Nome: Dideiodo amiodarone
• Sinónimos: (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]phenyl]methanone2-Butyl-3-benzofuranyl p-[2-(diethylamino)ethoxy]phenylketoneL 3937, (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]phenyl]methanone, Deiodoamiodarone, Ketone, 2-butyl-3-benzofuranyl p-[2-(diethylamino)ethoxy]phenyl, Ketone,2-butyl-3-benzofuranyl p-[2-(diethylamino)ethoxy]phenyl (7CI,8CI), L 3937, Methanone, (2-butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]phenyl]-

Descrição

Dideiodo amiodarone is a noncompetitive inhibitor of the enzyme, which is expressed in the human heart. It has been shown to interact with the benzofuran derivatives that are responsible for the antiarrhythmic effects of amiodarone. The inhibitory potency of dideiodo amiodarone is dose-dependent and constant. This drug has shown no competitive inhibition against any other analogs, such as quinidine or digitoxin. Dideiodo amiodarone inhibits the enzyme by binding to an allosteric site on the enzyme molecule. This site does not bind any other analogs, such as quinidine or digitoxin, and therefore it does not compete for this site.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 393.52 g/mol
• Fórmula: C₂₅H₃₁NO₃
• Pureza: Min. 95%
• Cor/forma: Clear Liquid
• InChI: InChI=1S/C25H31NO3/c1-4-7-11-23-24(21-10-8-9-12-22(21)29-23)25(27)19-13-15-20(16-14-19)28-18-17-26(5-2)6-3/h8-10,12-16H,4-7,11,17-18H2,1-3H3
• Chave InChI: InChIKey=PNZXBMCTFUFPLR-UHFFFAOYSA-N
• SMILES: CCCCc1oc2ccccc2c1C(=O)c1ccc(OCCN(CC)CC)cc1