Pepstatin A (Purity Higher than 90% by HPLC)

CAS: 26305-03-3

Ref. 3D-IPA-4397

Informação sobre produto

• Nome: Pepstatin A (Purity Higher than 90% by HPLC)
• Sinónimos: Pepstatin A, pepstatin A from microbial source, Pepstatin (microbial product), Isovaleryl-Val-Val-Sta-Ala-Sta-OH, N-(3-methylbutanoyl)-L-valyl-N-[(1S,2S)-4-{[(1S)-2-({(1S)-1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl}amino)-1-methyl-2-oxoethyl]amino}-2-hydroxy-1-(2-methylpropyl)-4-oxobutyl]-L-valinamide, (3S,4R)-3-hydroxy-4-[[(2R)-2-[[(3R,4S)-3-hydroxy-6-methyl-4-[[(2R)-3-methyl-2-[[(2R)-3-methyl-2-(3-methylbutanoylamino)butanoyl]amino]butanoyl]amino]heptanoyl]amino]propanoyl]amino]-6-methyl-heptanoic acid, Pepstatin

Descrição

Pepstatin A is a natural product that inhibits the activity of proteases, particularly chymotrypsin and trypsin. It binds to the active site of these enzymes, blocking access to their substrate. Pepstatin A has been shown to have synergistic effects with other drugs in vitro, such as dapsone and clindamycin. Pepstatin A has inhibitory properties against infectious diseases, including HIV-1 and HIV-2, influenza virus type A (H1N1), herpes simplex virus type 1 (HSV-1), human papilloma virus type 18 (HPV-18), hepatitis C virus (HCV) types 1a and 1b, as well as dengue fever virus. Pepstatin A is also effective in inhibiting polymerase chain reaction amplification of mitochondrial DNA from patients with mitochondrial disorders. The biological sample for this research was obtained from calf thymus tissue. The natural compound pepstatin A has

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 685.89 g/mol
• Fórmula: C₃₄H₆₃N₅O₉
• Pureza: Higher Than 90% By Hplc)