2-[(2-Chloroquinazolin-4-yl)amino]ethan-1-ol

CAS: 134517-34-3

Ref. 3D-JFA51734

Informação sobre produto

• Nome: 2-[(2-Chloroquinazolin-4-yl)amino]ethan-1-ol

Descrição

2-[(2-Chloroquinazolin-4-yl)amino]ethan-1-ol (CQAEE) is a prodrug that is enzymatically hydrolyzed in vivo to the active form CQAE. It is an inhibitor of carbonic anhydrase enzymes and has been shown to be more potent than amiodarone and less toxic than acetazolamide. CQAEE has been shown to be effective in vitro against human erythrocytes, homopolymers, and amiodarone, but not in vivo against congestive heart failure. The process of hydrolysis by enzymes causes the release of a carboxylic acid and ethylene glycol which are responsible for the observed therapeutic effects.

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• Marca: Biosynth

Propriedades químicas

• Peso molecular: 223.66 g/mol
• Fórmula: C₁₀H₁₀ClN₃O
• Pureza: Min. 95%