Informação sobre produto
- 2-[4(1H)-Pyridinylidene]-1H-indane-1,3(2H)-dione
- 2-pyridin-4(1H)-ylidene-1H-indene-1,3(2H)-dione
2-(4-Pyridyl)indane-1,3-dione is a cytotoxic agent that inhibits the growth of cancer cells. It has been shown to be selective against colon and breast cancers in laboratory testing. 2-(4-Pyridyl)indane-1,3-dione blocks the progression of cancer by inhibiting the synthesis of DNA. This drug also has anti-inflammatory properties that may be due to its ability to inhibit prostaglandin synthesis. The cytotoxicity of 2-(4-pyridyl)indane-1,3-dione was tested on HT29 colon cancer cells and MDA-MB231 breast cancer cells in vitro. The drug showed an IC50 value of 0.21±0.03 μM for HT29 cells and 0.22±0.02 μM for MDA-MB231 cells, which is indicative of its potency as a cytotoxic agent against these cell lines
Propriedades químicas
Consulta técnica sobre: 3D-KAA47899 2-(4-pyridyl)indane-1,3-dione
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