3-(2-Hydroxyphenyl)acrylaldehyde
CAS: 60125-23-7
Ref. 3D-KCA12523
1g | Descontinuado | ||
50mg | Descontinuado | ||
100mg | Descontinuado | ||
250mg | Descontinuado | ||
500mg | Descontinuado |
Informação sobre produto
- (2E)-3-(2-Hydroxyphenyl)-2-propenal
- (E)-3-(2-Hydroxyphenyl)acrylaldehyde
- 2-Propenal, 3-(2-hydroxyphenyl)-, (E)-
- 2-Propenal, 3-(2-hydroxyphenyl)-, (2E)-
- trans-2-Hydroxycinnamaldehyde
3-(2-Hydroxyphenyl)acrylaldehyde is an activated form of phenylacetic acid and is a potent inhibitor of angiogenesis, which is the formation of new blood vessels. It has been shown to inhibit the growth of cancer cells in vivo. 3-(2-Hydroxyphenyl)acrylaldehyde binds to DNA and inhibits the activity of transcription factors, such as nuclear factor kappa-B (NF-κB), which plays a role in inflammation. The compound also inhibits cyclin D1, which regulates cell cycle progression and cell proliferation. 3-(2-Hydroxyphenyl)acrylaldehyde has been shown to be effective against human colon cancer cells in vitro and sw620 cells in vivo.