Geissoschizine methyl ether

CAS: 60314-89-8

Ref. 3D-KCA31489

Informação sobre produto

• Nome: Geissoschizine methyl ether
• Sinónimos: Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethylidene-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)-, methyl ester, [2S-[2α(Z),3E,12bβ]]-, O-Methyl-16Z-geissoschizine, Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethylidene-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)-, methyl ester, (αZ,2S,3E,12bS)-, Corynan-16-carboxylic acid, 16,17,19,20-tetradehydro-17-methoxy-, methyl ester, (16Z,19E)-

Descrição

Geissoschizine methyl ether is a chemical compound that belongs to the group of 5-HT2C receptor antagonists. It is also known as geissoschizine methyl ether and uncaria. Geissoschizine methyl ether binds to the serotonin 5-HT2C receptor, which leads to an increase in intracellular calcium levels and subsequently neuronal death. In addition, this agent has been shown to inhibit voltage-dependent calcium channels, leading to a decrease in neurotransmitter release. The compound has also been shown to inhibit polymerase chain reaction (PCR) of DNA and RNA in vitro. This inhibition may be due to its ability to bind with basic proteins such as histones. Geissoschizine methyl ether also inhibits protein synthesis by binding with the ribosome at the peptidyl transferase site on the ribosome.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 366.46 g/mol
• Fórmula: C₂₂H₂₆N₂O₃
• Pureza: Min. 95%