Ethyl 3-(2,4-dimethoxyphenyl)-3-oxopropanoate

CAS: 60946-77-2

Ref. 3D-KCA94677

Informação sobre produto

• Nome: Ethyl 3-(2,4-dimethoxyphenyl)-3-oxopropanoate

Descrição

Ethyl 3-(2,4-dimethoxyphenyl)-3-oxopropanoate (EMPO) is a natural product that has been shown to inhibit estrogen receptor activity in breast cancer cells. It also inhibits the proliferation of these cells and induces apoptosis. EMPO is an estrogen receptor modulator that binds to the estrogen receptor and inhibits its activity by binding to its ligand (estrogen). The synthesis of EMPO starts with the oxidation of 2,4-dimethoxybenzaldehyde. This reaction is catalyzed by copper(II) acetate and can be performed using the cross-coupling technique. The lactonization step involves the conversion of EMPO into its lactone form. This reaction can be carried out through acidic hydrolysis or by heating it with base. The final step in this synthesis is to convert the lactone into a carboxylic acid with hydrochloric acid. EMPO has been shown to have potential as

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 252.26 g/mol
• Fórmula: C₁₃H₁₆O₅
• Pureza: Min. 95%