Domatinostat
CAS: 910462-43-0
Ref. 3D-KLB46243
| 5mg | A consultar | |
| 10mg | A consultar | |
| 25mg | A consultar | |
| 50mg | A consultar | |
| 100mg | A consultar |
Informação sobre produto
Domatinostat is a retinoid-related all-trans retinoic acid (ATRA) derivative. It is a low-molecular weight, water soluble molecule that can penetrate the cytosol of cells, where it binds to the retinoic acid receptor and inhibits cell growth. Domatinostat has been shown to be effective against prostate cancer cells in vitro and in animal models. This drug also shows cytostatic effects on fetal bovine kidney cells and is able to inhibit tumor growth in mice with skin cancer. Domatinostat induces apoptosis by inhibiting the phosphorylation of Akt and ERK1/2, which are proteins involved in regulating cell survival and proliferation pathways. Domatinostat has also been shown to be effective against urothelial carcinoma cells as well as bone cancer cells in vitro and in mice models.
Propriedades químicas
Consulta técnica sobre: 3D-KLB46243 Domatinostat
Se desejar solicitar um orçamento ou fazer uma encomenda, por favor, adicione os produtos ao seu carrinho e depois solicite um orçamento ou encomenda a partir do carrinho. É mais rápido, mais barato e poderá beneficiar-se dos descontos e outras vantagens disponíveis.
