2-Deoxy-D-glucose-6-phosphate
CAS: 3573-50-0
Ref. 3D-MD03848
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Informação sobre produto
- 2-Deoxy-D-arabino-hexose-6-phosphate
- D-arabino-Hexose, 2-deoxy-, 6-(dihydrogen phosphate)
- 2-Deoxy-D-glucose 6-phosphate
- 2-Deoxyglucose 6-phosphate
- D-arabino-Hexose, 2-deoxy-, 6-phosphate
- D-Glucose, 2-deoxy-, 6-phosphate
2-Deoxy-D-glucose-6-phosphate is a glucose analogue that is phosphorylated by hexokinase to 2-deoxy-D-glucose. It has been shown to inhibit the activity of enzymes involved in energy metabolism, such as atp synthase and dpp IV. This drug can also inhibit the synthesis of proteins and RNA by binding to response elements, which are DNA sequences that regulate gene expression. The 2-deoxy glucose analogue has been shown to be a potent inhibitor of ventricular myocardium contractility via its ability to reduce mitochondrial membrane potential.
Propriedades químicas
Consulta técnica sobre: 3D-MD03848 2-Deoxy-D-glucose-6-phosphate
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