Leptomycin A

CAS: 87081-36-5

Ref. 3D-MDA08136

Informação sobre produto

• Nome: Leptomycin A
• Marca: Biosynth
• Descrição: Leptomycin A is a Streptomyces-produced inhibitor, which is derived from the bacterium Streptomyces spiroverticillatus. It functions by specifically binding to and inhibiting the CRM1 (exportin 1), a nuclear export receptor. This action blocks the nuclear export of proteins that contain a leucine-rich nuclear export signal (NES), thereby leading to their accumulation within the nucleus. The inhibition of CRM1 disrupts various cellular processes, including cell cycle regulation and signal transduction pathways.

Propriedades químicas

• Peso molecular: 526.7 g/mol
• Fórmula: C₃₂H₄₆O₆
• Pureza: Min. 95%