4-Chloro-1-methyl-1H-indazole

CAS: 162502-53-6

Ref. 3D-MGA50253

Informação sobre produto

• Nome: 4-Chloro-1-methyl-1H-indazole
• Sinónimos: 1H-indazole, 4-chloro-1-methyl-

Descrição

4-Chloro-1-methyl-1H-indazole is an antagonist of the TRPV1 receptor. It is a benzyl derivative that has been shown to be a potent and selective antagonist of the TRPV1 receptor in vitro. 4-Chloro-1-methyl-1H-indazole binds to the TRPV1 receptor with high affinity and inhibits its activity. This leads to a decrease in the release of proinflammatory cytokines, such as IL6, TNFα, and IL8. 4-Chloro-1-methyl-1H-indazole also suppresses inflammation by inhibiting the production of reactive oxygen species (ROS) and nitric oxide (NO).

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 166.61 g/mol
• Fórmula: C₈H₇ClN₂
• Pureza: Min. 95%