TAPI-2

CAS: 187034-31-7

Ref. 3D-MHA03431

Informação sobre produto

• Nome: TAPI-2
• Marca: Biosynth
• Descrição: TAPI-2 is an inhibitor of ADAM-17 (also called TACE) and matrix metalloproteinases (MMPs). It acts as a broad-spectrum inhibitor of these enzymes. TAPI-2 prevents the shedding of tumor necrosis factor-alpha (TNF-α) from cell membranes and can sensitize cancer stem cells to the effects of chemotherapy such as 5-fluorouracil (5-FU) in vitro. It also blocks the phorbol ester-induced shedding of other cell surface proteins like TGF-α and β-amyloid precursor protein.

Propriedades químicas

• Peso molecular: 415.53 g/mol
• Fórmula: C₁₉H₃₇N₅O₅
• Pureza: Min. 95%