Informação sobre produto
5-Bromo-2-(2-methoxyethoxy)pyridine (BMP) is a compound that has been shown to have anticancer activity. BMP was found to have synergistic effects with doxorubicin and etoposide in vitro and in vivo, and also showed apoptotic cell death when introduced into cells. It has been found to be effective against a variety of tumor xenografts in mice, including sarcoma 180, Neuro 2A, Lewis lung carcinoma, and human colon cancer. The pharmacokinetic properties of BMP are not well understood as it is poorly absorbed from the gastrointestinal tract. However, it has been observed that BMP is expressed at high levels in cardiac tissue and tumor tissues. It has also been observed that BMP induces apoptosis by binding to the proapoptotic protein bax or bcl-2 proteins.
Propriedades químicas
Consulta técnica sobre: 3D-MIA96129 5-Bromo-2-(2-methoxyethoxy)pyridine
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