Boc-Leu-Gly-Arg-AMC

CAS: 65147-09-3

Ref. 3D-MLG-3102-V

Informação sobre produto

• Nome: Boc-Leu-Gly-Arg-AMC
• Sinónimos: t-Butyloxycarbonyl-L-Leucyl-Glycyl-L-Arginine 4-Methyl-Coumaryl-7-Amide Boc-Leu-Gly-Arg-MCA Boc-LGR-AMC
• Marca: Biosynth
• Descrição: Boc-Leu-Gly-Arg-AMC is a peptide that binds to the receptor for N-methyl-D-aspartate (NMDA) and inhibits the ion channel. It has been used as a research tool to study NMDA receptor interactions, as well as in cell biology and pharmacology. Boc-Leu-Gly-Arg-AMC is a high purity, ionic analog of glutamate that binds to the NMDA receptor without activating it, thereby inhibiting ion flow through the channel. This inhibition can be reversed by adding excess glutamate or glycine. The binding of this compound to the NMDA receptor has been shown to block activation of voltage gated calcium channels and reduce neuronal excitation, which may provide an alternative therapeutic strategy for controlling seizures or other neurological disorders.

Propriedades químicas

• Peso molecular: 601.69 g/mol
• Fórmula: C₂₉H₄₃N₇O₇
• Pureza: Min. 95%