N-Methylglucamine antimonate

CAS: 133-51-7

Ref. 3D-MM44354

Informação sobre produto

• Nome: N-Methylglucamine antimonate
• Sinónimos: 1-Deoxy-1-(methylamino)-D-glucitol antimonateMeglumine antimonate, 1-Deoxy-1-(methylamino)-D-glucitol, compound with antimonic acid (1:1), 1-Deoxy-1-(methylamino)glucitol antimonate(V), 2168-Rp, 2168Rp, 3-(Methylamino)-1-[4,4,4-Trihydroxy-2-(Hydroxymethyl)-3,5-Dioxa-4$L5-Stibacyclopent-1-Yl]Propane-1,2-Diol, <span class="text-smallcaps">D</span>-Glucitol, 1-deoxy-1-(methylamino)-, compd. with antimonic acid (HSbO₃) (1:1), <span class="text-smallcaps">D</span>-Glucitol, 1-deoxy-1-(methylamino)-, trioxoantimonate(1-), Antimonate (SbO₃^1-), hydrogen, compd. with 1-deoxy-1-(methylamino)-<span class="text-smallcaps">D</span>-glucitol (1:1), Antimonic acid (HSbO₃), compd. with <span class="text-smallcaps">D</span>-1-deoxy-1-(methylamino)glucitol (1:1), D-Glucitol, 1-deoxy-1-(methylamino)-, compd. with antimonic acid (1:1), D-Glucitol, 1-deoxy-1-(methylamino)-, trioxoantimonate(1-), Glucantim, Glucantime, Glucitol, 1-deoxy-1-(methylamino)-, antimonate(V), Glucitol, 1-deoxy-1-(methylamino)-, compd. with antimonic acid (1:1), D-, Glucitol, 1-deoxy-1-(methylamino)-, compd. with antimonic acid (HSbO₃) (1:1), <span class="text-smallcaps">D</span>-, Meglumine antimonate, Meglumine antimoniate, Methylglucamine antimonate, Protostib, Rp 2168
• CAS: 133-51-7

Descrição

N-Methylglucamine antimonate is a drug that is used to treat cutaneous leishmaniasis. It is not active against the visceral form of the disease. The drug binds to antimony in a 1:1 stoichiometry and inhibits the polymerase chain reaction (PCR) in the parasite, which prevents DNA replication and transcription. This inhibition leads to cell death and eventual elimination of Leishmania parasites from the host. N-Methylglucamine antimonate is only effective against Leishmania parasites and has no effect on other bacteria or viruses, such as bowel disease. The drug can be given orally or intravenously, but should not be given to patients with bowel diseases because this may lead to intestinal ulceration or perforation.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 365.98 g/mol
• Fórmula: C₇H₁₇NO₅·HSbO₃
• Pureza: Min. 95%
• Cor/forma: White Powder