2-(1-(Ethylsulfonyl)azetidin-3-ylidene)acetonitrile
CAS: 1187595-85-2
Ref. 3D-MXB59585
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Informação sobre produto
- 2-[1-(Ethanesulfonyl)azetidin-3-ylidene]acetonitrile
- 2-[1-(Ethylsulfonyl)-3-azetidinylidene]acetonitrile
- Acetonitrile, 2-[1-(ethylsulfonyl)-3-azetidinylidene]-
- [1-(Ethylsulfonyl)azetidin-3-ylidene]acetonitrile
The synthesis of 2-(1-(ethylsulfonyl)azetidin-3-ylidene)acetonitrile (2) from 2-chloroaniline (1) and benzyl bromide (4) is a one-pot reaction that proceeds in good yields. The synthesis of 2-(1-(ethylsulfonyl)azetidin-3-ylidene)acetonitrile (2) from 2-chloroaniline (1) and benzyl bromide (4) is a one-pot reaction that proceeds in good yields. The Suzuki coupling reaction between the tert butylbenzene derivative 3 and the borane 4,5-diboronic ester 5 leads to the desired product 6 in high yield. The coupling can be carried out at room temperature without the need for additional solvents or heating. This efficient method provides an efficient approach to the synthesis of baricitin
Propriedades químicas
Consulta técnica sobre: 3D-MXB59585 2-(1-(Ethylsulfonyl)azetidin-3-ylidene)acetonitrile
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