3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt

CAS: 133525-01-6

Ref. 3D-NA06316

Informação sobre produto

• Nome: 3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt
• Sinónimos: AZT GlucuronideZidovudine glucuronide sodium salt, 3-Azido-3-deoxythymidine -D-glucuronide, Sodium Salt

Descrição

3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt is an antiviral and anticancer agent that inhibits the synthesis of DNA, RNA, and protein. It has shown to be effective against a variety of viruses including HIV-1, herpes simplex virus type 1, influenza A virus, vaccinia virus, and vesicular stomatitis virus. 3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt also inhibits the growth of cancer cells in vitro. This drug is a modified nucleoside with a phosphoramidite backbone and a 3'-azido group at one end. The other end contains a beta D glucuronic acid moiety. The modifications allow for the inhibition of DNA synthesis by blocking the incorporation of deoxyribonucleotides into DNA chains.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 465.35 g/mol
• Fórmula: C₁₆H₂₀N₅NaO₁₀
• Pureza: Min. 95%
• Cor/forma: Powder