(2R)-2-Hydroxypentanedioic acid
CAS: 13095-47-1
Ref. 3D-NAA09547
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Informação sobre produto
(2R)-2-Hydroxypentanedioic acid is a metabolite of 2-hydroxyglutarate that is produced in the metabolism of glucose. This compound has been shown to be elevated in gliomas and may serve as a diagnostic marker for this type of cancer. A mutation in isocitrate dehydrogenase, an enzyme that catalyzes the conversion of isocitrate to alpha-ketoglurate, has been shown to be associated with gliomas. This mutation leads to accumulation of (2R)-2-hydroxypentanedioic acid and increases the risk for this type of cancer. The elevated levels of (2R)-2-hydroxypentanedioic acid can be used as a biomarker for disease activity and diagnosis.
Propriedades químicas
Consulta técnica sobre: 3D-NAA09547 (2R)-2-Hydroxypentanedioic acid
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