8-Bromo-2'-deoxyguanosine

CAS: 13389-03-2

Ref. 3D-NB05782

Informação sobre produto

• Nome: 8-Bromo-2'-deoxyguanosine
• Sinónimos: 8-Bromo-2'-deoxy-D-guanosine, 2-amino-8-bromo-9-(2-deoxypentofuranosyl)-3,9-dihydro-6H-purin-6-one, Guanosine, 8-bromo-2′-deoxy-, NSC 105830
• CAS: 13389-03-2

Descrição

8-Bromo-2'-deoxyguanosine is a reactive brominated compound that has been shown to stabilize DNA strands. The effects of 8-bromo-2'-deoxyguanosine on the stability of DNA are due to the steric interactions between the bromine and amines in the DNA backbone, which prevent nucleophilic attack. 8-Bromo-2'-deoxyguanosine is an antihistamine, but it has also been used as a precursor for other drugs such as zidovudine, an antiviral drug used in HIV/AIDS therapy. It has also been proposed as a potential treatment for atherosclerosis.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 346.14 g/mol
• Fórmula: C₁₀H₁₂BrN₅O₄
• Pureza: Min. 90 Area-%
• Cor/forma: Off-White Powder