N6-Benzoyl-3'-deoxyadenosine

CAS: 76902-49-3

Ref. 3D-NB31303

Informação sobre produto

• Nome: N6-Benzoyl-3'-deoxyadenosine
• Sinónimos: N6-Benzoyl-3’-Deoxyadenosine

Descrição

N6-Benzoyl-3'-deoxyadenosine is a nucleoside analogue that is used as a substrate for DNA polymerase. The efficiency of this compound has been shown to be higher than other nucleotides. In addition, N6-Benzoyl-3'-deoxyadenosine has been shown to be an efficient donor in the ligation reaction and can also act as a competitive inhibitor of topoisomerase II. N6-Benzoyl-3'-deoxyadenosine is a scissile substrate for DNA topoisomerase II and cleaves at the same site as dATP. This compound has been shown to be active against both Gram-positive bacteria and Mycobacterium tuberculosis with high selectivity.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 355.35 g/mol
• Fórmula: C₁₇H₁₇N₅O₄
• Pureza: Min. 95%
• InChI: InChI=1S/C17H17N5O4/c23-7-11-6-12(24)17(26-11)22-9-20-13-14(18-8-19-15(13)22)21-16(25)10-4-2-1-3-5-10/h1-5,8-9,11-12,17,23-24H,6-7H2,(H,18,19,21,25)/t11-,12+,17+/m0/s1
• Chave InChI: InChIKey=GNPRDDYSJSKPJF-XWCIJXRUSA-N
• SMILES: O=C(Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)C[C@H]1O)c1ccccc1