N6-Benzoyl-5'-chloro-5'-deoxy-2',3'-O-isopropylideneadenosine

Ref. 3D-NB46326

Informação sobre produto

• Nome: N6-Benzoyl-5'-chloro-5'-deoxy-2',3'-O-isopropylideneadenosine
• Marca: Biosynth
• Descrição: N6-Benzoyl-5'-chloro-5'-deoxy-2',3'-O-isopropylideneadenosine is a novel nucleoside that has the potential to be a therapeutic agent for cancer and antiviral therapy. It is an analog of adenosine that inhibits viral replication by inhibiting the viral enzyme RNA-dependent DNA polymerase. N6-Benzoyl-5'-chloro-5'-deoxy-2',3'-O-isopropylideneadenosine also inhibits tumor growth by inducing apoptosis. The compound has been shown to inhibit human leukemia cells in vitro, as well as mouse leukemia cells in vivo. This novel nucleoside is synthesized through a two step process starting with 5'-chloroadenosine and converting it to 5'-chloroinosidine with potassium cyanide, followed by deoxygenation at the 6 position with benzoyl chloride and sodium hydroxide.

Propriedades químicas

• Pureza: Min. 95%