6-Chloro-9-(2'-deoxy-β-D-ribofuranosyl)purine

CAS: 4594-45-0

Ref. 3D-NC06422

Informação sobre produto

• Nome: 6-Chloro-9-(2'-deoxy-β-D-ribofuranosyl)purine
• Sinónimos: 6-Chloropurine-2'-deoxyriboside6-Cl-Deoxyriboside, 6-Chloro-9-(2'-deoxyribofuranosyl) purine, 6-Chloropurine-2'-Deoxyriboside
• CAS: 4594-45-0

Descrição

6-Chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is a nucleoside analogue that inhibits the replication of the hepatitis C virus. It binds to the viral RNA polymerase and blocks the synthesis of viral RNA, thereby preventing infection. This drug also has antiviral activity against HIV and herpes simplex viruses. The antiviral effect is due to its ability to inhibit phosphatases and carboxylates, which are involved in the initiation of mRNA transcription and protein translation, respectively. 6-Chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is metabolized by deoxyadenosine kinase into 6-chloropurine ribonucleotide, which can be converted into other purines.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 270.68 g/mol
• Fórmula: C₁₀H₁₁ClN₄O₃
• Pureza: Min. 95%
• Cor/forma: Powder