6-Chloro-3'-deoxy-3'-fluoroinosine

Ref. 3D-NC15615

Informação sobre produto

• Nome: 6-Chloro-3'-deoxy-3'-fluoroinosine

Descrição

6-Chloro-3'-deoxy-3'-fluoroinosine (6-Cl-dF) is an analog of the nucleotide base, adenosine. It has been shown to be effective in the treatment of cancer and HIV infections. 6-Cl-dF inhibits DNA synthesis by inhibiting the activity of ribonucleotide reductase and DNA polymerase, which are enzymes that are required for DNA replication. 6-Cl-dF has been shown to inhibit viral replication by blocking reverse transcriptase (an enzyme necessary for viral replication). This drug has also been shown to have antiangiogenic properties.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 288.66 g/mol
• Fórmula: C₁₀H₁₀ClFN₄O₃
• Pureza: Min. 95%
• InChI: InChI=1S/C10H10ClFN4O3/c11-8-6-9(14-2-13-8)16(3-15-6)10-7(18)5(12)4(1-17)19-10/h2-5,7,10,17-18H,1H2/t4-,5?,7+,10-/m1/s1
• Chave InChI: InChIKey=YPDBGBGFACYTFL-TXDIQVCSSA-N
• SMILES: OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@@H](O)C1F