2-Chloropurine

CAS: 1681-15-8

Ref. 3D-NC15936

Informação sobre produto

• Nome: 2-Chloropurine
• Sinónimos: 2-chloro-5H-purine, 2-chloro-7H-purine, 1H-Purine, 2-chloro-, 2-chloro-9H-purine

Descrição

2-Chloropurine is an organic compound that is a purine analog and a prodrug of 6-mercaptopurine. It has shown to be effective in the treatment of various types of cancer, including leukemia and polycystic ovarian syndrome. 2-Chloropurine is metabolized by hydrolysis to 6-mercaptopurine, which can then be converted into thioguanine nucleotide (TGN) by the action of hydroxide solution. TGN can react with adenine nucleotide to form guanine nucleotide (GMP). 2-Chloropurine has been shown to have anti-inflammatory effects and may be used as a therapeutic agent for inflammatory diseases such as bladder inflammation.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 154.56 g/mol
• Fórmula: C₅H₃ClN₄
• Pureza: Min. 95%
• Cor/forma: White to pale yellow solid.
• InChI: InChI=1S/C5H3ClN4/c6-5-7-1-3-4(10-5)9-2-8-3/h1-2H,(H,7,8,9,10)
• Chave InChI: InChIKey=JBMBVWROWJGFMG-UHFFFAOYSA-N
• SMILES: Clc1ncc2[nH]cnc2n1