2'-Deoxy-8-oxoguanosine

CAS: 88847-89-6

Ref. 3D-ND06344

Informação sobre produto

• Nome: 2'-Deoxy-8-oxoguanosine
• Sinónimos: 8-Hydroxy-2'-deoxyguanosine8-Oxo-2'-deoxyguanosine8-Oxo-dG2'-Deoxy-8-oxo-D-guanosine
• Marca: Biosynth
• Descrição: 2'-Deoxy-8-oxoguanosine (8-OHdG) is a product of oxidative DNA damage. The presence of 8-OHdG in urine has been used to detect and measure the degree of oxidative DNA damage in humans and animals, which may be linked to cancer and aging. When 8-OHdG is excreted into urine, it can react with other molecules such as protein or inorganic phosphorus, causing more oxidative DNA damage. 2'-Deoxy-8-oxoguanosine has also been shown to cause cell toxicity by damaging the cell's squamous epithelium, leading to cancer.For the 15N5 labelled version please check ND09970.

Propriedades químicas

• Peso molecular: 283.25 g/mol
• Fórmula: C₁₀H₁₃N₅O₅
• Pureza: Min. 95 Area-%
• Cor/forma: White Powder